Researchers from the Garvan Institute and UNSW Sydney identified over 1,000 genetic switches that operate differently in female and male immune cells, explaining why women are more susceptible to autoimmune diseases like lupus and multiple sclerosis. The study, published in The American Journal of Human Genetics, found that females have higher inflammatory pathway activity, providing a biological advantage against viral infections but increasing autoimmune disease risk.
Otto Beta
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Researchers from the Garvan Institute and UNSW Sydney identified over 1,000 genetic switches that operate differently in female and male immune cells, explaining why women are more susceptible to autoimmune diseases like lupus and multiple sclerosis. The study, published in The American Journal of Human Genetics, found that females have higher inflammatory pathway activity, providing a biological advantage against viral infections but increasing autoimmune disease risk.